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The kinetic basis of peptide exchange catalysis by HLA-DM
The mechanism by which the peptide exchange factor HLA-DM catalyzes peptide loading onto structurally homologous class II MHC proteins is an outstanding problem in antigen presentation. The peptide-loading reaction of class II MHC proteins is complex and includes conformational changes in both empty...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60074/ https://ncbi.nlm.nih.gov/pubmed/11606721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211439398 |
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