The kinetic basis of peptide exchange catalysis by HLA-DM
The mechanism by which the peptide exchange factor HLA-DM catalyzes peptide loading onto structurally homologous class II MHC proteins is an outstanding problem in antigen presentation. The peptide-loading reaction of class II MHC proteins is complex and includes conformational changes in both empty...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211439398 |
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