The kinetic basis of peptide exchange catalysis by HLA-DM

The mechanism by which the peptide exchange factor HLA-DM catalyzes peptide loading onto structurally homologous class II MHC proteins is an outstanding problem in antigen presentation. The peptide-loading reaction of class II MHC proteins is complex and includes conformational changes in both empty...

詳細記述

書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Zarutskie, Jennifer A., Busch, Robert, Zavala-Ruiz, Zarixia, Rushe, Mia, Mellins, Elizabeth D., Stern, Lawrence J.
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2001
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.211439398
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