DCLAK11, a multi-tyrosine kinase inhibitor, exhibits potent antitumor and antiangiogenic activity in vitro

by Guo, Xiao-bin, Chen, Xian-jie, Tong, Lin-jiang, Peng, Xia, Huang, Min, Liu, Hong-chun, Liu, Hong, Ding, Jian
Published in Acta Pharmacol Sin (2015)

MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition

by Dai, Mei, Miao, Ze-Hong, Ren, Xuan, Tong, Lin-Jiang, Yang, Na, Li, Ting, Lin, Li-Ping, Shen, Yue-Mao, Ding, Jian
Published 2010

GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms

by Xie, Hua, Qin, Yu-xin, Zhou, Yun-long, Tong, Lin-jiang, Lin, Li-ping, Geng, Mei-yu, Duan, Wen-hu, Ding, Jian
Published 2009

Characterization of the conversion between CD133(+) and CD133(-) cells in colon cancer SW620 cell line

by Feng, Jian-Ming, Miao, Ze-Hong, Jiang, Yi, Chen, Yi, Li, Jia-Xin, Tong, Lin-Jiang, Zhang, Jin, Huang, Yi-Ran, Ding, Jian
Published 2012

Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent...

by Lai, Meng-zhen, Song, Pei-ran, Dou, Dou, Diao, Yan-yan, Tong, Lin-jiang, Zhang, Tao, Xie, Hua, Li, Hong-lin, Ding, Jian
Published in Acta Pharmacol Sin (2019)

Anti-proliferative effects, cell cycle G(2)/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines

by Lu, Da Yong, Huang, Min, Xu, Cheng Hui, Yang, Wei Yi, Hu, Chao Xin, Lin, Li Ping, Tong, Lin Jiang, Li, Mei Hong, Lu, Wei, Zhang, Xiong Wen, Ding, Jian
Published 2005

Naphthalimides Induce G(2) Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells

by Zhu, Hong, Miao, Ze-Hong, Huang, Min, Feng, Jian-Ming, Zhang, Zhi-Xiang, Lu, Jin-Jian, Cai, Yu-Jun, Tong, Lin-Jiang, Xu, Yu-Fang, Qian, Xu-Hong, Ding, Jian
Published 2009

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

by Zhou, Zhao-Li, Luo, Zhi-Guo, Yu, Bing, Jiang, Yi, Chen, Yi, Feng, Jian-Ming, Dai, Mei, Tong, Lin-Jiang, Li, Zheng, Li, Yuan-Chao, Ding, Jian, Miao, Ze-Hong
Published 2010

Drug Transporter-independent Liver Cancer Cell Killing by a Marine Steroid Methyl Spongoate via Apoptosis Induction

by Jiang, Yi, Miao, Ze-Hong, Xu, Lei, Yu, Bing, Gong, Jing-Xu, Tong, Lin-Jiang, Chen, Yi, Zhou, Zhao-Li, Liu, Hong-Chun, Wang, Yi, Guo, Yue-Wei, Ding, Jian
Published 2011

Establishment of platform for screening insulin-like growth factor-1 receptor inhibitors and evaluation of novel inhibitors

by Tong, Lin-jiang, Xie, Hua, Peng, Ting, Liu, Xiao-feng, Xin, Xian-liang, Huang, Xun, Chen, Si-meng, Liu, Hong-yan, Li, Hong-lin, Geng, Mei-yu, Yin, Ming, Ding, Jian
Published 2011

Identification of DW532 as a novel anti-tumor agent targeting both kinases and tubulin

by Peng, Ting, Wu, Jian-rui, Tong, Lin-jiang, Li, Meng-yuan, Chen, Fang, Leng, Yi-xin, Qu, Rong, Han, Kun, Su, Yi, Chen, Yi, Duan, Wen-hu, Xie, Hua, Ding, Jian
Published 2014

DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo

by Li, Meng-yuan, Lv, Yong-cong, Tong, Lin-jiang, Peng, Ting, Qu, Rong, Zhang, Tao, Sun, Yi-ming, Chen, Yi, Wei, Li-xin, Geng, Mei-yu, Duan, Wen-hu, Xie, Hua, Ding, Jian
Published in Acta Pharmacol Sin (2016)

C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis

by Chen, Zhuo, Tong, Lin-jiang, Tang, Bai-you, Liu, Hong-yan, Wang, Xin, Zhang, Tao, Cao, Xian-wen, Chen, Yi, Li, Hong-lin, Qian, Xu-hong, Xu, Yu-fang, Xie, Hua, Ding, Jian
Published in Acta Pharmacol Sin (2018)

Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R

by Liu, Ying-Qiang, Wang, Ya-Nan, Lu, Xiao-Yun, Tong, Lin-Jiang, Li, Yan, Zhang, Tao, Xun, Qiu-Ju, Feng, Fang, Chen, Yu-Zhe, Su, Yi, Shen, Yan-Yan, Chen, Yi, Geng, Mei-Yu, Ding, Ke, Li, Yan-Li, Xie, Hua, Ding, Jian
Published in Acta Pharmacol Sin (2018)

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution

by He, Jin-Xue, Wang, Meng, Huan, Xia-Juan, Chen, Chuan-Huizi, Song, Shan-Shan, Wang, Ying-Qing, Liao, Xue-Mei, Tan, Cun, He, Qian, Tong, Lin-Jiang, Wang, Yu-Ting, Li, Xiao-Hua, Su, Yi, Shen, Yan-Yan, Sun, Yi-Ming, Yang, Xin-Ying, Chen, Yi, Gao, Zhi-Wei, Chen, Xiao-Yan, Xiong, Bing, Lu, Xiu-Lian, Ding, Jian, Yang, Chun-Hao, Miao, Ze-Hong
Published in Oncotarget (2016)