Anti-proliferative effects, cell cycle G(2)/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines

BACKGROUND: Anticancer bisdioxopiperazines, including ICRF-154, razoxane (Raz, ICRF-159) and ICRF-193, are a family of anticancer agents developed in the UK, especially targeting metastases of neoplasms. Two other bisdioxopiperazine derivatives, probimane (Pro) and MST-16, were synthesized at the Sh...

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Main Authors: Lu, Da Yong, Huang, Min, Xu, Cheng Hui, Yang, Wei Yi, Hu, Chao Xin, Lin, Li Ping, Tong, Lin Jiang, Li, Mei Hong, Lu, Wei, Zhang, Xiong Wen, Ding, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180833/
https://ncbi.nlm.nih.gov/pubmed/15963241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-5-11
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