C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis

The fibroblast growth factor receptors (FGFRs) are increasingly considered attractive targets for therapeutic cancer intervention due to their roles in tumor metastasis and angiogenesis. Here, we identified a new selective FGFR inhibitor, C11, and assessed its antitumor activities. C11 was a selecti...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Chen, Zhuo, Tong, Lin-jiang, Tang, Bai-you, Liu, Hong-yan, Wang, Xin, Zhang, Tao, Cao, Xian-wen, Chen, Yi, Li, Hong-lin, Qian, Xu-hong, Xu, Yu-fang, Xie, Hua, Ding, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786402/
https://ncbi.nlm.nih.gov/pubmed/30487650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0191-7
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