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FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7

Cancer-associated fibroblasts (CAFs), as the activated fibroblasts in the tumor stroma, are important modifiers of tumour progression. In the present study, we observed that azoxymethane and dextran sodium sulfate treatments induced increasingly severe colorectal mucosal inflammation and the intratu...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Bai, Yu-Pan, Shang, Kun, Chen, Huan, Ding, Fei, Wang, Zhen, Liang, Chen, Xu, Ye, Sun, Meng-Hong, LI, Ying-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637995/
https://ncbi.nlm.nih.gov/pubmed/26183471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12745
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