Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer

BACKGROUND: Grb2-associated binder 2 (Gab2), a scaffolding adaptor protein, has recently been implicated in cancer progression. However, the role of Gab2 in the progression and metastasis of colorectal cancer (CRC) remains unclear. METHODS: Gab2 expression was assessed in CRC patient specimens as we...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ding, Chenbo, Luo, Junmin, Li, Longmei, Li, Shanshan, Yang, Liwen, Pan, Hongfei, Liu, Qianyi, Qin, Huan, Chen, Chao, Feng, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709914/
https://ncbi.nlm.nih.gov/pubmed/26754532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0280-0
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