Mitochondrial Adaptations to Oxidative Stress Confer Resistance to Apoptosis in Lymphoma Cells

Por Wilkinson, Sarah T., Tome, Margaret E., Briehl, Margaret M.
Publicado em 2012

Hydrogen peroxide signaling is required for glucocorticoid-induced apoptosis in lymphoma cells

Por Tome, Margaret E., Jaramillo, Melba C., Briehl, Margaret M.
Publicado em 2011

P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery

Por Davis, Thomas P., Sanchez-Covarubias, Lucy, Tome, Margaret E.
Publicado no Adv Pharmacol (2014)

Mitochondria are the primary source of the H(2)O(2) signal for glucocorticoid-induced apoptosis of lymphoma cells

Por TOME, MARGARET E., LEE, KRISTY, JARAMILLO, MELBA C., BRIEHL, MARGARET M.
Publicado em 2012

MnTE-2-PyP(5+) acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics and enhance the response to chemotherapy in lymphoma cells

Por Jaramillo, Melba C., Briehl, Margaret M., Batinic-Haberle, Ines, Tome, Margaret E.
Publicado no Free Radic Biol Med (2015)

A Strategy for Full Interrogation of Prognostic Gene Expression Patterns: Exploring the Biology of Diffuse Large B Cell Lymphoma

Por Rimsza, Lisa M., Unger, Joseph M., Tome, Margaret E., LeBlanc, Michael L.
Publicado em 2011

Mitochondria and redox homeostasis as chemotherapeutic targets

Por Briehl, Margaret M., Tome, Margaret E., Wilkinson, Sarah T., Jaramillo, Melba C., Lee, Kristy
Publicado no Biochem Soc Trans (2014)

The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma

Por LEE, KRISTY, HART, MATTHEW R., BRIEHL, MARGARET M., MAZAR, ANDREW P., TOME, MARGARET E.
Publicado em 2014

Increased manganese superoxide dismutase expression or treatment with a manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells

Por Jaramillo, Melba C., Frye, Jennifer B., Crapo, James D., Briehl, Margaret M., Tome, Margaret E.
Publicado em 2009

Increased cytochrome c correlates with poor survival in aggressive lymphoma

Por WILKINSON, SARAH T., JOHNSON, DAVID B.F., TARDIF, HEATHER L., TOME, MARGARET E., BRIEHL, MARGARET M.
Publicado em 2010

Manganese Porphyrin, MnTE-2-PyP(5+), Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells

Por Jaramillo, Melba C., Briehl, Margaret M., Crapo, James D., Haberle, Ines Batinic, Tome, Margaret E.
Publicado em 2012

Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels

Por Tome, Margaret E., Schaefer, Charles P., Jacobs, Leigh M., Zhang, Yifeng, Herndon, Joseph M., Matty, Fabian O., Davis, Thomas P.
Publicado no J Neurochem (2015)

P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain

Por Tome, Margaret E, Herndon, Joseph M, Schaefer, Charles P, Jacobs, Leigh M, Zhang, Yifeng, Jarvis, Chelsea K, Davis, Thomas P
Publicado no J Cereb Blood Flow Metab (2016)

Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis

Por Goldman, Aaron, Chen, Hwu Dau Rw, Roesly, Heather B., Hill, Kimberly A., Tome, Margaret E., Dvorak, Bohuslav, Bernstein, Harris, Dvorak, Katerina
Publicado em 2011

Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance

Por TOME, MARGARET E., FRYE, JENNIFER B., COYLE, DONNA L., JACOBSON, ELAINE L., SAMULITIS, BETTY K., DVORAK, KATERINA, DORR, ROBERT T., BRIEHL, MARGARET M.
Publicado em 2012

Copper Chelator ATN-224 Induces Peroxynitrite-Dependent Cell Death in Hematological Malignancies

Por Lee, Kristy, Briehl, Margaret M., Mazar, Andrew P., Batinic-Haberle, Ines, Reboucas, Julio S., Glinsmann-Gibson, Betty, Rimsza, Lisa M., Tome, Margaret E.
Publicado em 2013

A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis

Por Tome, Margaret E., Johnson, David B. F., Rimsza, Lisa M., Roberts, Robin A., Grogan, Thomas M., Miller, Thomas P., Oberley, Larry W., Briehl, Margaret M.
Publicado em 2005