Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis

Barrett's esophagus (BE) is a premalignant condition, where normal squamous epithelium is replaced by intestinal epithelium. BE is associated with an increased risk of developing esophageal adenocarcinoma (EAC). However, the BE cell of origin is not clear. We hypothesize that BE tissue originat...

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Bibliographische Detailangaben
Hauptverfasser: Goldman, Aaron, Chen, Hwu Dau Rw, Roesly, Heather B., Hill, Kimberly A., Tome, Margaret E., Dvorak, Bohuslav, Bernstein, Harris, Dvorak, Katerina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043651/
https://ncbi.nlm.nih.gov/pubmed/21127259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00461.2010
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