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Mitochondria and redox homeostasis as chemotherapeutic targets

Characteristics of cancer cells include a more oxidized redox environment, metabolic reprogramming, and apoptosis resistance. Our studies with a lymphoma model have explored connections between the cellular redox environment and cancer cell phenotypes. Alterations seen in lymphoma cells made resista...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Briehl, Margaret M., Tome, Margaret E., Wilkinson, Sarah T., Jaramillo, Melba C., Lee, Kristy
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564327/
https://ncbi.nlm.nih.gov/pubmed/25109983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140087
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