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Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels
Drug delivery to the brain for the treatment of pathologies with a CNS component is a significant clinical challenge. P-glycoprotein (PgP), a drug efflux pump in the endothelial cell membrane, is a major factor in preventing therapeutics from crossing the blood-brain barrier (BBB). Identifying PgP r...
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| Foilsithe in: | J Neurochem |
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| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490986/ https://ncbi.nlm.nih.gov/pubmed/25832806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13106 |
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