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P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery
The primary function of the blood-brain barrier (BBB) /neurovascular unit is to protect the CNS from potentially harmful xenobiotic substances and maintain CNS homeostasis. Restricted access to the CNS is maintained via a combination of tight junction proteins as well as a variety of efflux and infl...
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| 出版年: | Adv Pharmacol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301584/ https://ncbi.nlm.nih.gov/pubmed/25307213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2014.06.009 |
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