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Transporters at CNS Barrier Sites: Obstacles or Opportunities for Drug Delivery?

The blood-brain barrier (BBB) and blood-cerebrospinal fluid (BCSF) barriers are critical determinants of CNS homeostasis. Additionally, the BBB and BCSF barriers are formidable obstacles to effective CNS drug delivery. These brain barrier sites express putative influx and efflux transporters that pr...

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Detalhes bibliográficos
Main Authors: Sanchez-Covarrubias, Lucy, Slosky, Lauren M., Thompson, Brandon J., Davis, Thomas P., Ronaldson, Patrick T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913737/
https://ncbi.nlm.nih.gov/pubmed/23789948
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