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Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels
Drug delivery to the brain for the treatment of pathologies with a CNS component is a significant clinical challenge. P-glycoprotein (PgP), a drug efflux pump in the endothelial cell membrane, is a major factor in preventing therapeutics from crossing the blood-brain barrier (BBB). Identifying PgP r...
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| Publicat a: | J Neurochem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490986/ https://ncbi.nlm.nih.gov/pubmed/25832806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13106 |
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