Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

Por Baynes, Caroline, Healey, Catherine S, Pooley, Karen A, Scollen, Serena, Luben, Robert N, Thompson, Deborah J, Pharoah, Paul DP, Easton, Douglas F, Ponder, Bruce AJ, Dunning, Alison M
Publicado em 2007

Telomere Length Shows No Association with BRCA1 and BRCA2 Mutation Status

Por Killick, Emma, Tymrakiewicz, Malgorzata, Cieza-Borrella, Clara, Smith, Paula, Thompson, Deborah J., Pooley, Karen A., Easton, Doug F., Bancroft, Elizabeth, Page, Elizabeth, Leongamornlert, Daniel, Kote-Jarai, Zsofia, Eeles, Rosalind A.
Publicado em 2014

Most common ‘sporadic’ cancers have a significant germline genetic component

Por Lu, Yi, Ek, Weronica E., Whiteman, David, Vaughan, Thomas L., Spurdle, Amanda B., Easton, Douglas F., Pharoah, Paul D., Thompson, Deborah J., Dunning, Alison M., Hayward, Nicholas K., Chenevix-Trench, Georgia, Macgregor, Stuart
Publicado no Hum Mol Genet (2014)

Identification of common variants in the SHBG gene affecting sex hormone binding globulin levels and breast cancer risk in postmenopausal women

Por Thompson, Deborah J, Healey, Catherine S, Baynes, Caroline, Kalmyrzaev, Bolot, Ahmed, Shahana, Dowsett, Mitch, Folkerd, Elizabeth, Luben, Robert N, Cox, David, Ballinger, Dennis, Pharoah, Paul DP, Ponder, Bruce AJ, Dunning, Alison M, Easton, Douglas F
Publicado em 2008

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

Por Thompson, Deborah J, Leach, Martin O, Kwan-Lim, Gek, Gayther, Simon A, Ramus, Susan J, Warsi, Iqbal, Lennard, Fiona, Khazen, Michael, Bryant, Emilie, Reed, Sadie, Boggis, Caroline RM, Evans, D Gareth, Eeles, Rosalind A, Easton, Douglas F, Warren, Ruth ML
Publicado em 2009

Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women

Por Prescott, Jennifer, Thompson, Deborah J., Kraft, Peter, Chanock, Stephen J., Audley, Tina, Brown, Judith, Leyland, Jean, Folkerd, Elizabeth, Doody, Deborah, Hankinson, Susan E., Hunter, David J., Jacobs, Kevin B., Dowsett, Mitch, Cox, David G., Easton, Douglas F., De Vivo, Immaculata
Publicado em 2012

Genetic Variants in ER Cofactor Genes and Endometrial Cancer Risk

Por Li, Yuqing, Low, Hui-Qi, Foo, Jia Nee, Darabi, Hatef, Einarsdόttir, Kristjana, Humphreys, Keith, Spurdle, Amanda, Easton, Douglas F., Thompson, Deborah J., Dunning, Alison M., Pharoah, Paul D. P., Czene, Kamila, Chia, Kee Seng, Hall, Per, Liu, Jianjun
Publicado em 2012

Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size

Por Li, Jingmei, Foo, Jia Nee, Schoof, Nils, Varghese, Jajini S., Fernandez-Navarro, Pablo, Gierach, Gretchen L., Quek, Swee Tian, Hartman, Mikael, Nord, Silje, Kristensen, Vessela N., Pollán, Marina, Figueroa, Jonine D., Thompson, Deborah J., Li, Yi, Khor, Chiea Chuen, Humphreys, Keith, Liu, Jianjun, Czene, Kamila, Hall, Per
Publicado em 2013

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis

Por Nead, Kevin T., Sharp, Stephen J., Thompson, Deborah J., Painter, Jodie N., Savage, David B., Semple, Robert K., Barker, Adam, Perry, John R. B., Attia, John, Dunning, Alison M., Easton, Douglas F., Holliday, Elizabeth, Lotta, Luca A., O’Mara, Tracy, McEvoy, Mark, Pharoah, Paul D. P., Scott, Rodney J., Spurdle, Amanda B., Langenberg, Claudia, Wareham, Nicholas J., Scott, Robert A.
Publicado no J Natl Cancer Inst (2015)

A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

Por Painter, Jodie N., Kaufmann, Susanne, O’Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B., Edwards, Stacey L.
Publicado no Am J Hum Genet (2016)

Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study

Por Healey, Catherine S., Ahmed, Shahana, O’Mara, Tracy A., Ferguson, Kaltin, Lambrechts, Diether, Garcia-Dios, Diego A., Vergote, Ignace, Amant, Frederic, Howarth, Kimberley, Gorman, Maggie, Hodgson, Shirley, Tomlinson, Ian, Yang, Hannah P., Lissowska, Jolanta, Brinton, Louise A., Chanock, Stephen, Garcia-Closas, Montserrat, Hall, Per, Liu, Jianjun, Shah, Mitul, Pharoah, Paul D.P., Thompson, Deborah J., Rebbeck, Timothy R., Strom, Brian L., Dunning, Alison M., Easton, Douglas F., Spurdle, Amanda B.
Publicado em 2011

Mammographic breast density and breast cancer: evidence of a shared genetic basis

Por Varghese, Jajini S, Thompson, Deborah J, Michailidou, Kyriaki, Lindström, Sara, Turnbull, Clare, Brown, Judith, Leyland, Jean, Warren, Ruth ML, Luben, Robert N, Loos, Ruth J, Wareham, Nicholas J, Rommens, Johanna, Paterson, Andrew D, Martin, Lisa J, Vachon, Celine M, Scott, Christopher G, Atkinson, Elizabeth J, Couch, Fergus J, Apicella, Carmel, Southey, Melissa C, Stone, Jennifer, Li, Jingmei, Eriksson, Louise, Czene, Kamila, Boyd, Norman F, Hall, Per, Hopper, John L, Tamimi, Rulla M, Rahman, Nazneen, Easton, Douglas F
Publicado em 2012

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

Por Spurdle, Amanda B., Thompson, Deborah J., Ahmed, Shahana, Ferguson, Kaltin, Healey, Catherine S., O’Mara, Tracy, Walker, Logan C., Montgomery, Stephen B., Dermitzakis, Emmanouil T., Fahey, Paul, Montgomery, Grant, Webb, Penelope M., Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander, Lambrechts, Diether, Coenegrachts, Lieve, Vergote, Ignace, Amant, Frederic, Salvesen, Helga B., Trovik, Jone, Njolstad, Tormund S, Helland, Harald, Scott, Rodney, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Tomlinson, Ian, Gorman, Maggie, Howarth, Kimberley, Hodgson, Shirley, Garcia-Closas, Montserrat, Wentzensen, Nicolas, Yang, Hannah, Chanock, Stephen, Hall, Per, Czene, Kamila, Liu, Jianjun, Li, Jingmei, Shu, Xiao-Ou, Zheng, Wei, Long, Jirong, Xiang, Yong-Bing, Shah, Mitul, Morrison, Jonathan, Michailidou, Kyriaki, Pharoah, Paul P., Dunning, Alison M., Easton, Douglas F.
Publicado em 2011

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

Por Lindström, Sara, Thompson, Deborah J., Paterson, Andrew D., Li, Jingmei, Gierach, Gretchen L., Scott, Christopher, Stone, Jennifer, Douglas, Julie A., dos-Santos-Silva, Isabel, Fernandez-Navarro, Pablo, Verghase, Jajini, Smith, Paula, Brown, Judith, Luben, Robert, Wareham, Nicholas J., Loos, Ruth J.F., Heit, John A., Pankratz, V. Shane, Norman, Aaron, Goode, Ellen L., Cunningham, Julie M., deAndrade, Mariza, Vierkant, Robert A., Czene, Kamila, Fasching, Peter A., Baglietto, Laura, Southey, Melissa C., Giles, Graham G., Shah, Kaanan P., Chan, Heang-Ping, Helvie, Mark A., Beck, Andrew H., Knoblauch, Nicholas W., Hazra, Aditi, Hunter, David J., Kraft, Peter, Pollan, Marina, Figueroa, Jonine D., Couch, Fergus J., Hopper, John L., Hall, Per, Easton, Douglas F., Boyd, Norman F., Vachon, Celine M., Tamimi, Rulla M.
Publicado no Nat Commun (2014)

Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures

Por Stone, Jennifer, Thompson, Deborah J., dos-Santos-Silva, Isabel, Scott, Christopher, Tamimi, Rulla M., Lindstrom, Sara, Kraft, Peter, Hazra, Aditi, Li, Jingmei, Eriksson, Louise, Czene, Kamila, Hall, Per, Jensen, Matt, Cunningham, Julie, Olson, Janet E., Purrington, Kristen, Couch, Fergus J., Brown, Judith, Leyland, Jean, Warren, Ruth M. L., Luben, Robert N., Khaw, Kay-Tee, Smith, Paula, Wareham, Nicholas J., Jud, Sebastian M., Heusinger, Katharina, Beckmann, Matthias W., Douglas, Julie A., Shah, Kaanan P., Chan, Heang-Ping, Helvie, Mark A., Le Marchand, Loic, Kolonel, Laurence N., Woolcott, Christy, Maskarinec, Gertraud, Haiman, Christopher, Giles, Graham G., Baglietto, Laura, Krishnan, Kavitha, Southey, Melissa C., Apicella, Carmel, Andrulis, Irene L., Knight, Julia A., Ursin, Giske, Grenaker Alnaes, Grethe I., Kristensen, Vessela N., Borresen-Dale, Anne-Lise, Gram, Inger Torhild, Bolla, Manjeet K., Wang, Qin, Michailidou, Kyriaki, Dennis, Joe, Simard, Jacques, Paroah, Paul, Dunning, Alison M., Easton, Douglas F., Fasching, Peter A., Pankratz, V. Shane, Hopper, John, Vachon, Celine M.
Publicado no Cancer Res (2015)

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

Por O’Mara, Tracy A, Glubb, Dylan M, Painter, Jodie N, Cheng, Timothy, Dennis, Joe, Attia, John, Holliday, Elizabeth G, McEvoy, Mark, Scott, Rodney J, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Shah, Mitul, Ahmed, Shahana, Healey, Catherine S, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Fasching, Peter A, Hein, Alexander, Beckmann, Matthias W, Ekici, Arif B, Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Dürst, Matthias, Runnebaum, Ingo, Hillemanns, Peter, Dörk, Thilo, Lambrechts, Diether, Depreeuw, Jeroen, Annibali, Daniela, Amant, Frederic, Zhao, Hui, Goode, Ellen L, Dowdy, Sean C, Fridley, Brooke L, Winham, Stacey J, Salvesen, Helga B, Njølstad, Tormund S, Trovik, Jone, Werner, Henrica MJ, Tham, Emma, Liu, Tao, Mints, Miriam, Bolla, Manjeet K, Michailidou, Kyriaki, Tyrer, Jonathan P, Wang, Qin, Hopper, John L, Peto, Julian, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Pharoah, Paul D P, Dunning, Alison M, Tomlinson, Ian, Easton, Douglas F, Thompson, Deborah J, Spurdle, Amanda B
Publicado no Endocr Relat Cancer (2015)

Genetic risk score Mendelian randomization shows obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer

Por Painter, Jodie N, O’Mara, Tracy A, Marquart, Louise, Webb, Penelope M, Attia, John, Medland, Sarah E, Cheng, Timothy, Dennis, Joe, Holliday, Elizabeth G, McEvoy, Mark, Scott, Rodney J, Ahmed, Shahana, Healey, Catherine S, Shah, Mitul, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley V, Beckmann, Matthias W, Ekici, Arif B, Fasching, Peter A, Hein, Alexander, Rübner, Matthias, Czene, Kamila, Darabi, Hatef, Hall, Per, Li, Jingmei, Dörk, Thilo, Dürst, Matthias, Hillemanns, Peter, Runnebaum, Ingo B, Amant, Frederic, Annibali, Daniela, Depreeuw, Jeroen, Lambrechts, Diether, Neven, Patrick, Cunningham, Julie M, Dowdy, Sean C, Goode, Ellen L, Fridley, Brooke L, Winham, Stacey J, Njølstad, Tormund S, Salvesen, Helga B, Trovik, Jone, Werner, Henrica MJ, Ashton, Katie A, Otton, Geoffrey, Proietto, Anthony, Mints, Miriam, Tham, Emma, Bolla, Manjeet K, Michailidou, Kyriaki, Wang, Qin, Tyrer, Jonathan P, Hopper, John L, Peto, Julian, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Pharoah, Paul D P, Tomlinson, Ian, Dunning, Alison M, Easton, Douglas F, Thompson, Deborah J, Spurdle, Amanda B
Publicado no Cancer Epidemiol Biomarkers Prev (2016)

Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk

Por Vachon, Celine M., Scott, Christopher G., Fasching, Peter A., Hall, Per, Tamimi, Rulla M., Li, Jingmei, Stone, Jennifer, Apicella, Carmel, Odefrey, Fabrice, Gierach, Gretchen L., Jud, Sebastian M., Heusinger, Katharina, Beckmann, Matthias W., Pollan, Marina, Fernández-Navarro, Pablo, González-Neira, Anna, Benítez, Javier, van Gils, Carla H., Lokate, Mariëtte, Onland-Moret, N. Charlotte, Peeters, Petra H.M., Brown, Judith, Leyland, Jean, Varghese, Jajini S., Easton, Douglas F., Thompson, Deborah J., Luben, Robert N., Warren, Ruth ML, Wareham, Nicholas J., Loos, Ruth JF, Khaw, Kay-Tee, Ursin, Giske, Lee, Eunjung, Gayther, Simon A., Ramus, Susan J., Eeles, Rosalind A., Leach, Martin O., Kwan-Lim, Gek, Couch, Fergus J., Giles, Graham G., Baglietto, Laura, Krishnan, Kavitha, Southey, Melissa C., Le Marchand, Loic, Kolonel, Laurence N., Woolcott, Christy, Maskarinec, Gertraud, Haiman, Christopher A, Walker, Kate, Johnson, Nichola, McCormack, Valerie A., Biong, Margarethe, Alnæs, Grethe I.G., Gram, Inger Torhild, Kristensen, Vessela N., Børresen-Dale, Anne-Lise, Lindström, Sara, Hankinson, Susan E., Hunter, David J., Andrulis, Irene L., Knight, Julia A., Boyd, Norman F., Figueroa, Jonine D., Lissowska, Jolanta, Wesolowska, Ewa, Peplonska, Beata, Bukowska, Agnieszka, Reszka, Edyta, Liu, JianJun, Eriksson, Louise, Czene, Kamila, Audley, Tina, Wu, Anna H., Pankratz, V. Shane, Hopper, John L., dos-Santos-Silva, Isabel
Publicado em 2012

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

Por Perry, John R.B., Hsu, Yi-Hsiang, Chasman, Daniel I., Johnson, Andrew D., Elks, Cathy, Albrecht, Eva, Andrulis, Irene L., Beesley, Jonathan, Berenson, Gerald S., Bergmann, Sven, Bojesen, Stig E., Bolla, Manjeet K., Brown, Judith, Buring, Julie E., Campbell, Harry, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Corre, Tanguy, Couch, Fergus J., Cox, Angela, Czene, Kamila, D'adamo, Adamo Pio, Davies, Gail, Deary, Ian J., Dennis, Joe, Easton, Douglas F., Engelhardt, Ellen G., Eriksson, Johan G., Esko, Tõnu, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Fraser, Abigail, Garcia-Closas, Montse, Gasparini, Paolo, Gieger, Christian, Giles, Graham, Guenel, Pascal, Hägg, Sara, Hall, Per, Hayward, Caroline, Hopper, John, Ingelsson, Erik, Kardia, Sharon L.R., Kasiman, Katherine, Knight, Julia A., Lahti, Jari, Lawlor, Debbie A., Magnusson, Patrik K.E., Margolin, Sara, Marsh, Julie A., Metspalu, Andres, Olson, Janet E., Pennell, Craig E., Polasek, Ozren, Rahman, Iffat, Ridker, Paul M., Robino, Antonietta, Rudan, Igor, Rudolph, Anja, Salumets, Andres, Schmidt, Marjanka K., Schoemaker, Minouk J., Smith, Erin N., Smith, Jennifer A., Southey, Melissa, Stöckl, Doris, Swerdlow, Anthony J., Thompson, Deborah J., Truong, Therese, Ulivi, Sheila, Waldenberger, Melanie, Wang, Qin, Wild, Sarah, Wilson, James F, Wright, Alan F., Zgaga, Lina, Ong, Ken K., Murabito, Joanne M., Karasik, David, Murray, Anna
Publicado em 2014

Rare coding variants and X-linked loci associated with age at menarche

Por Lunetta, Kathryn L., Day, Felix R., Sulem, Patrick, Ruth, Katherine S., Tung, Joyce Y., Hinds, David A., Esko, Tõnu, Elks, Cathy E., Altmaier, Elisabeth, He, Chunyan, Huffman, Jennifer E., Mihailov, Evelin, Porcu, Eleonora, Robino, Antonietta, Rose, Lynda M., Schick, Ursula M., Stolk, Lisette, Teumer, Alexander, Thompson, Deborah J., Traglia, Michela, Wang, Carol A., Yerges-Armstrong, Laura M., Antoniou, Antonis C., Barbieri, Caterina, Coviello, Andrea D., Cucca, Francesco, Demerath, Ellen W., Dunning, Alison M., Gandin, Ilaria, Grove, Megan L., Gudbjartsson, Daniel F., Hocking, Lynne J., Hofman, Albert, Huang, Jinyan, Jackson, Rebecca D., Karasik, David, Kriebel, Jennifer, Lange, Ethan M., Lange, Leslie A., Langenberg, Claudia, Li, Xin, Luan, Jian'an, Mägi, Reedik, Morrison, Alanna C., Padmanabhan, Sandosh, Pirie, Ailith, Polasek, Ozren, Porteous, David, Reiner, Alex P., Rivadeneira, Fernando, Rudan, Igor, Sala, Cinzia F., Schlessinger, David, Scott, Robert A., Stöckl, Doris, Visser, Jenny A., Völker, Uwe, Vozzi, Diego, Wilson, James G., Zygmunt, Marek, Boerwinkle, Eric, Buring, Julie E., Crisponi, Laura, Easton, Douglas F., Hayward, Caroline, Hu, Frank B., Liu, Simin, Metspalu, Andres, Pennell, Craig E., Ridker, Paul M., Strauch, Konstantin, Streeten, Elizabeth A., Toniolo, Daniela, Uitterlinden, André G., Ulivi, Sheila, Völzke, Henry, Wareham, Nicholas J., Wellons, Melissa, Franceschini, Nora, Chasman, Daniel I., Thorsteinsdottir, Unnur, Murray, Anna, Stefansson, Kari, Murabito, Joanne M., Ong, Ken K., Perry, John R. B.
Publicado no Nat Commun (2015)