Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer

Por O’Mara, Tracy A., Crosbie, Emma J.
Publicado no Br J Cancer (2020)

ECGene: A Literature‐Based Knowledgebase of Endometrial Cancer Genes

Por Zhao, Min, Liu, Yining, O'Mara, Tracy A
Publicado no Hum Mutat (2016)

Editorial: Establishing Genetic Pleiotropy to Identify Common Pharmacological Agents for Common Diseases

Por O’Mara, Tracy A., Batra, Jyotsna, Glubb, Dylan
Publicado no Front Pharmacol (2019)

Meta-analysis of gene expression studies in endometrial cancer identifies gene expression profiles associated with aggressive disease and patient outcome

Por O’Mara, Tracy A., Zhao, Min, Spurdle, Amanda B.
Publicado no Sci Rep (2016)

Analysis of Promoter-Associated Chromatin Interactions Reveals Biologically Relevant Candidate Target Genes at Endometrial Cancer Risk Loci

Por O’Mara, Tracy A., Spurdle, Amanda B., Glubb, Dylan M.
Publicado no Cancers (Basel) (2019)

Enhancing the Promise of Drug Repositioning through Genetics

Por Pritchard, Jayne-Louise E., O’Mara, Tracy A., Glubb, Dylan M.
Publicado no Front Pharmacol (2017)

The Association of CYP19A1 Variation with Circulating Estradiol and Aromatase Inhibitor Outcome: Can CYP19A1 Variants Be Used to Predict Treatment Efficacy?

Por Glubb, Dylan M., O'Mara, Tracy A., Shamsani, Jannah, Spurdle, Amanda B.
Publicado no Front Pharmacol (2017)

Assessing the Role of Selenium in Endometrial Cancer Risk: A Mendelian Randomization Study

Por Kho, Pik Fang, Glubb, Dylan M., Thompson, Deborah J., Spurdle, Amanda B., O'Mara, Tracy A.
Publicado no Front Oncol (2019)

ROR1 is upregulated in endometrial cancer and represents a novel therapeutic target

Por Liu, Dongli, Gunther, Kate, Enriquez, Luis A., Daniels, Benjamin, O’Mara, Tracy A., Tang, Katrina, Spurdle, Amanda B., Ford, Caroline E.
Publicado no Sci Rep (2020)

seXY: a tool for sex inference from genotype arrays

Por Qian, David C, Busam, Jonathan A, Xiao, Xiangjun, O’Mara, Tracy A, Eeles, Rosalind A, Schumacher, Frederick R, Phelan, Catherine M, Amos, Christopher I
Publicado no Bioinformatics (2017)

Co-existence of leiomyomas, adenomyosis and endometriosis in women with endometrial cancer

Por Johnatty, Sharon E., Stewart, Colin J. R., Smith, Deborah, Nguyen, Anthony, O’ Dwyer, John, O’Mara, Tracy A., Webb, Penelope M., Spurdle, Amanda B.
Publicado no Sci Rep (2020)

Endometrial cancer risk and survival by tumor MMR status

Por Nagle, Christina M., O'Mara, Tracy A., Tan, Yen, Buchanan, Daniel D., Obermair, Andreas, Blomfield, Penny, Quinn, Michael A., Webb, Penelope M., Spurdle, Amanda B.
Publicado no J Gynecol Oncol (2018)

A plugin for the Ensembl Variant Effect Predictor that uses MaxEntScan to predict variant spliceogenicity

Por Shamsani, Jannah, Kazakoff, Stephen H, Armean, Irina M, McLaren, Will, Parsons, Michael T, Thompson, Bryony A, O’Mara, Tracy A, Hunt, Sarah E, Waddell, Nicola, Spurdle, Amanda B
Publicado no Bioinformatics (2019)

The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

Por Russell, Holly, Kedzierska, Katarzyna, Buchanan, Daniel D., Thomas, Rachael, Tham, Emma, Mints, Miriam, Keränen, Anne, Giles, Graham G., Southey, Melissa C., Milne, Roger L., Tomlinson, Ian, Church, David, Spurdle, Amanda B., O’Mara, Tracy A., Lewis, Annabelle
Publicado no Clin Epigenetics (2020)

Progesterone receptor gene variants and risk of endometrial cancer

Por O'Mara, Tracy A., Fahey, Paul, Ferguson, Kaltin, Marquart, Louise, Lambrechts, Diether, Despierre, Evelyn, Vergote, Ignace, Amant, Frederic, Hall, Per, Liu, Jianjun, Czene, Kamila, Rebbeck, Timothy R., Ahmed, Shahana, Dunning, Alison M., Gregory, Catherine S., Shah, Mitul, Webb, Penelope M., Spurdle, Amanda B.
Publicado em 2011

Using human genetics to understand the disease impacts of testosterone in men and women

Por Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R.B.
Publicado no Nat Med (2020)

A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

Por Painter, Jodie N., Kaufmann, Susanne, O’Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B., Edwards, Stacey L.
Publicado no Am J Hum Genet (2016)

Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study

Por Healey, Catherine S., Ahmed, Shahana, O’Mara, Tracy A., Ferguson, Kaltin, Lambrechts, Diether, Garcia-Dios, Diego A., Vergote, Ignace, Amant, Frederic, Howarth, Kimberley, Gorman, Maggie, Hodgson, Shirley, Tomlinson, Ian, Yang, Hannah P., Lissowska, Jolanta, Brinton, Louise A., Chanock, Stephen, Garcia-Closas, Montserrat, Hall, Per, Liu, Jianjun, Shah, Mitul, Pharoah, Paul D.P., Thompson, Deborah J., Rebbeck, Timothy R., Strom, Brian L., Dunning, Alison M., Easton, Douglas F., Spurdle, Amanda B.
Publicado em 2011

Non-coding RNAs underlie genetic predisposition to breast cancer

Por Moradi Marjaneh, Mahdi, Beesley, Jonathan, O’Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L., French, Juliet D.
Publicado no Genome Biol (2020)

Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers

Por Walker, Logan C, Marquart, Louise, Pearson, John F, Wiggins, George A R, O'Mara, Tracy A, Parsons, Michael T, Barrowdale, Daniel, McGuffog, Lesley, Dennis, Joe, Benitez, Javier, Slavin, Thomas P, Radice, Paolo, Frost, Debra, Godwin, Andrew K, Meindl, Alfons, Schmutzler, Rita Katharina, Isaacs, Claudine, Peshkin, Beth N, Caldes, Trinidad, Hogervorst, Frans BL, Lazaro, Conxi, Jakubowska, Anna, Montagna, Marco, Chen, Xiaoqing, Offit, Kenneth, Hulick, Peter J, Andrulis, Irene L, Lindblom, Annika, Nussbaum, Robert L, Nathanson, Katherine L, Chenevix-Trench, Georgia, Antoniou, Antonis C, Couch, Fergus J, Spurdle, Amanda B
Publicado no Eur J Hum Genet (2017)