Mammographic breast density and breast cancer: evidence of a shared genetic basis

Percent mammographic breast density (PMD) is a strong heritable risk factor for breast cancer. However, the pathways through which this risk is mediated are still unclear. To explore whether PMD and breast cancer have a shared genetic basis, we identified genetic variants most strongly associated wi...

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Huvudupphovsmän: Varghese, Jajini S, Thompson, Deborah J, Michailidou, Kyriaki, Lindström, Sara, Turnbull, Clare, Brown, Judith, Leyland, Jean, Warren, Ruth ML, Luben, Robert N, Loos, Ruth J, Wareham, Nicholas J, Rommens, Johanna, Paterson, Andrew D, Martin, Lisa J, Vachon, Celine M, Scott, Christopher G, Atkinson, Elizabeth J, Couch, Fergus J, Apicella, Carmel, Southey, Melissa C, Stone, Jennifer, Li, Jingmei, Eriksson, Louise, Czene, Kamila, Boyd, Norman F, Hall, Per, Hopper, John L, Tamimi, Rulla M, Rahman, Nazneen, Easton, Douglas F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378688/
https://ncbi.nlm.nih.gov/pubmed/22266113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3295
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