Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

BACKGROUND: Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong risk factors for breast cancer and increase discrimination of risk models. Understanding their joint contribution will be important...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Breast Cancer Res
Main Authors: Vachon, Celine M., Scott, Christopher G., Tamimi, Rulla M., Thompson, Deborah J., Fasching, Peter A., Stone, Jennifer, Southey, Melissa C., Winham, Stacey, Lindström, Sara, Lilyquist, Jenna, Giles, Graham G., Milne, Roger L., MacInnis, Robert J., Baglietto, Laura, Li, Jingmei, Czene, Kamila, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Haeberle, Lothar, Eriksson, Mikael, Kraft, Peter, Luben, Robert, Wareham, Nick, Olson, Janet E., Norman, Aaron, Polley, Eric C., Maskarinec, Gertraud, Le Marchand, Loic, Haiman, Christopher A., Hopper, John L., Couch, Fergus J., Easton, Douglas F., Hall, Per, Chatterjee, Nilanjan, Garcia-Closas, Montse
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2019
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532188/
https://ncbi.nlm.nih.gov/pubmed/31118087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1138-8
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