Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

BACKGROUND: Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong risk factors for breast cancer and increase discrimination of risk models. Understanding their joint contribution will be important...

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書誌詳細
出版年:Breast Cancer Res
主要な著者: Vachon, Celine M., Scott, Christopher G., Tamimi, Rulla M., Thompson, Deborah J., Fasching, Peter A., Stone, Jennifer, Southey, Melissa C., Winham, Stacey, Lindström, Sara, Lilyquist, Jenna, Giles, Graham G., Milne, Roger L., MacInnis, Robert J., Baglietto, Laura, Li, Jingmei, Czene, Kamila, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Haeberle, Lothar, Eriksson, Mikael, Kraft, Peter, Luben, Robert, Wareham, Nick, Olson, Janet E., Norman, Aaron, Polley, Eric C., Maskarinec, Gertraud, Le Marchand, Loic, Haiman, Christopher A., Hopper, John L., Couch, Fergus J., Easton, Douglas F., Hall, Per, Chatterjee, Nilanjan, Garcia-Closas, Montse
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532188/
https://ncbi.nlm.nih.gov/pubmed/31118087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1138-8
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