Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

BACKGROUND: Mammographic breast density, adjusted for age and body mass index, and a polygenic risk score (PRS), comprised of common genetic variation, are both strong risk factors for breast cancer and increase discrimination of risk models. Understanding their joint contribution will be important...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res
Prif Awduron: Vachon, Celine M., Scott, Christopher G., Tamimi, Rulla M., Thompson, Deborah J., Fasching, Peter A., Stone, Jennifer, Southey, Melissa C., Winham, Stacey, Lindström, Sara, Lilyquist, Jenna, Giles, Graham G., Milne, Roger L., MacInnis, Robert J., Baglietto, Laura, Li, Jingmei, Czene, Kamila, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Haeberle, Lothar, Eriksson, Mikael, Kraft, Peter, Luben, Robert, Wareham, Nick, Olson, Janet E., Norman, Aaron, Polley, Eric C., Maskarinec, Gertraud, Le Marchand, Loic, Haiman, Christopher A., Hopper, John L., Couch, Fergus J., Easton, Douglas F., Hall, Per, Chatterjee, Nilanjan, Garcia-Closas, Montse
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532188/
https://ncbi.nlm.nih.gov/pubmed/31118087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1138-8
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