Simplified breast risk tool integrating questionnaire risk factors, mammographic density, and polygenic risk score: development and validation

BACKGROUND: Clinical use of breast cancer risk prediction requires simplified models. We evaluate a simplified version of the validated Rosner-Colditz model and add percent mammographic density (MD) and polygenic risk score (PRS), to assess performance from ages 45–74. We validate using the Mayo Mam...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Rosner, Bernard, Tamimi, Rulla M., Kraft, Peter, Gao, Chi, Mu, Yi, Scott, Christopher, Winham, Stacey J., Vachon, Celine M., Colditz, Graham A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026588/
https://ncbi.nlm.nih.gov/pubmed/33277321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-20-0900
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