Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case–control study

BACKGROUND: No prior study to our knowledge has examined the joint contribution of a polygenic risk score (PRS), mammographic density (MD), and postmenopausal endogenous hormone levels—all well-confirmed risk factors for invasive breast cancer—to existing breast cancer risk prediction models. METHOD...

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Publicado en:PLoS Med
Main Authors: Zhang, Xuehong, Rice, Megan, Tworoger, Shelley S., Rosner, Bernard A., Eliassen, A. Heather, Tamimi, Rulla M., Joshi, Amit D., Lindstrom, Sara, Qian, Jing, Colditz, Graham A., Willett, Walter C., Kraft, Peter, Hankinson, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122802/
https://ncbi.nlm.nih.gov/pubmed/30180161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002644
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