Identification of common variants in the SHBG gene affecting sex hormone binding globulin levels and breast cancer risk in postmenopausal women

BACKGROUND: Circulating levels of sex hormone-binding globulin (SHBG) are inversely associated with breast cancer risk in post-menopausal women. Three polymorphisms within the SHBG gene have been reported to affect SHBG levels, but there has been no systematic attempt to identify other such variants...

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Hoofdauteurs: Thompson, Deborah J, Healey, Catherine S, Baynes, Caroline, Kalmyrzaev, Bolot, Ahmed, Shahana, Dowsett, Mitch, Folkerd, Elizabeth, Luben, Robert N, Cox, David, Ballinger, Dennis, Pharoah, Paul DP, Ponder, Bruce AJ, Dunning, Alison M, Easton, Douglas F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660245/
https://ncbi.nlm.nih.gov/pubmed/19064566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0734
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