Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

INTRODUCTION: Certain rare, familial mutations in the ATM, BRCA1, BRCA2, CHEK2 or TP53 genes increase susceptibility to breast cancer but it has not, until now, been clear whether common polymorphic variants in the same genes also increase risk. METHODS: We have attempted a comprehensive, single nuc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Baynes, Caroline, Healey, Catherine S, Pooley, Karen A, Scollen, Serena, Luben, Robert N, Thompson, Deborah J, Pharoah, Paul DP, Easton, Douglas F, Ponder, Bruce AJ, Dunning, Alison M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868915/
https://ncbi.nlm.nih.gov/pubmed/17428325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1669
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki