Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

INTRODUCTION: Certain rare, familial mutations in the ATM, BRCA1, BRCA2, CHEK2 or TP53 genes increase susceptibility to breast cancer but it has not, until now, been clear whether common polymorphic variants in the same genes also increase risk. METHODS: We have attempted a comprehensive, single nuc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baynes, Caroline, Healey, Catherine S, Pooley, Karen A, Scollen, Serena, Luben, Robert N, Thompson, Deborah J, Pharoah, Paul DP, Easton, Douglas F, Ponder, Bruce AJ, Dunning, Alison M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2007
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868915/
https://ncbi.nlm.nih.gov/pubmed/17428325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1669
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