BRCA1, TP53, and CHEK2 Germline Mutations in Uterine Serous Carcinoma

BACKGROUND: Uterine serous carcinoma (USC) is not recognized as part of any defined hereditary cancer syndrome, and its association with hereditary breast and ovarian carcinoma and Lynch syndrome are uncertain. METHODS: Using targeted capture and massively parallel genomic sequencing, we assessed 15...

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Auteurs principaux: Pennington, Kathryn P., Walsh, Tom, Lee, Ming, Pennil, Christopher, Novetsky, Akiva P., Agnew, Kathy J., Thornton, Anne, Garcia, Rochelle, Mutch, David, King, Mary-Claire, Goodfellow, Paul, Swisher, Elizabeth M.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966566/
https://ncbi.nlm.nih.gov/pubmed/22811390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27720
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