Loss of function germline mutations in RAD51D in women with ovarian carcinoma

OBJECTIVE: RAD51D, a gene in the Fanconi Anemia-BRCA homologous recombination pathway, has recently been shown to harbor germline mutations responsible for ovarian carcinoma in multiply affected families. We aimed to extend these results to ovarian carcinoma in the general population. METHODS: We se...

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Hauptverfasser: Wickramanayake, Anneka, Bernier, Greta, Pennil, Christopher, Casadei, Silvia, Agnew, Kathy J, Stray, Sunday M., Mandell, Jessica, Garcia, Rochelle L., Walsh, Tom, King, Mary-Claire, Swisher, Elizabeth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905744/
https://ncbi.nlm.nih.gov/pubmed/22986143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.09.009
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