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Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing
Inherited loss-of-function mutations in the tumor suppressor genes BRCA1, BRCA2, and multiple other genes predispose to high risks of breast and/or ovarian cancer. Cancer-associated inherited mutations in these genes are collectively quite common, but individually rare or even private. Genetic testi...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906584/ https://ncbi.nlm.nih.gov/pubmed/20616022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007983107 |
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