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Inherited Mutations in Women with Ovarian Carcinoma

IMPORTANCE: Germline mutations in BRCA1 and BRCA2 are relatively common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime risk of these cancers, but the frequency and relevance of inherited mutations in other genes is less well characterized. O...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Norquist, Barbara M., Harrell, Maria I., Brady, Mark F., Walsh, Tom, Lee, Ming K., Gulsuner, Suleyman, Bernards, Sarah S., Casadei, Silvia, Yi, Qian, Burger, Robert A., Chan, John K., Davidson, Susan A., Mannel, Robert S., DiSilvestro, Paul A., Lankes, Heather A., Ramirez, Nilsa C., King, Mary Claire, Swisher, Elizabeth M., Birrer, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845939/
https://ncbi.nlm.nih.gov/pubmed/26720728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.5495
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