Inherited Mutations in Women with Ovarian Carcinoma

IMPORTANCE: Germline mutations in BRCA1 and BRCA2 are relatively common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime risk of these cancers, but the frequency and relevance of inherited mutations in other genes is less well characterized. O...

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Vydáno v:JAMA Oncol
Hlavní autoři: Norquist, Barbara M., Harrell, Maria I., Brady, Mark F., Walsh, Tom, Lee, Ming K., Gulsuner, Suleyman, Bernards, Sarah S., Casadei, Silvia, Yi, Qian, Burger, Robert A., Chan, John K., Davidson, Susan A., Mannel, Robert S., DiSilvestro, Paul A., Lankes, Heather A., Ramirez, Nilsa C., King, Mary Claire, Swisher, Elizabeth M., Birrer, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845939/
https://ncbi.nlm.nih.gov/pubmed/26720728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.5495
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