Inherited Mutations in Women with Ovarian Carcinoma

IMPORTANCE: Germline mutations in BRCA1 and BRCA2 are relatively common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime risk of these cancers, but the frequency and relevance of inherited mutations in other genes is less well characterized. O...

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Pubblicato in:JAMA Oncol
Autori principali: Norquist, Barbara M., Harrell, Maria I., Brady, Mark F., Walsh, Tom, Lee, Ming K., Gulsuner, Suleyman, Bernards, Sarah S., Casadei, Silvia, Yi, Qian, Burger, Robert A., Chan, John K., Davidson, Susan A., Mannel, Robert S., DiSilvestro, Paul A., Lankes, Heather A., Ramirez, Nilsa C., King, Mary Claire, Swisher, Elizabeth M., Birrer, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845939/
https://ncbi.nlm.nih.gov/pubmed/26720728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.5495
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