Somatic Mosaic Mutations in PPM1D and TP53 in the Blood of Women With Ovarian Carcinoma

IMPORTANCE: Somatic mosaic mutations in PPM1D have been reported in patients with breast cancer, lung cancer, and ovarian cancer (OC), but cause or effect has not been established. OBSERVATIONS: To test the hypothesis that somatic mosaic mutations are associated with chemotherapy exposure, we used m...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Swisher, Elizabeth M., Harrell, Maria I., Norquist, Barbara M., Walsh, Tom, Brady, Mark, Lee, Ming, Hershberg, Robert, Kalli, Kimberly R., Lankes, Heather, Konnick, Eric Q., Pritchard, Colin C., Monk, Bradley J., Chan, John K., Burger, Robert, Kaufmann, Scott H., Birrer, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865293/
https://ncbi.nlm.nih.gov/pubmed/26847329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.6053
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