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Somatic TP53 Mutations in the Era of Genome Sequencing

Amid the complexity of genetic alterations in human cancer, TP53 mutation appears as an almost invariant component, representing by far the most frequent genetic alteration overall. Compared with previous targeted sequencing studies, recent integrated genomics studies offer a less biased view of TP5...

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Veröffentlicht in:Cold Spring Harb Perspect Med
Hauptverfasser: Hainaut, Pierre, Pfeifer, Gerd P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088513/
https://ncbi.nlm.nih.gov/pubmed/27503997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026179
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