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Somatic TP53 Mutations in the Era of Genome Sequencing

Amid the complexity of genetic alterations in human cancer, TP53 mutation appears as an almost invariant component, representing by far the most frequent genetic alteration overall. Compared with previous targeted sequencing studies, recent integrated genomics studies offer a less biased view of TP5...

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Publicat a:Cold Spring Harb Perspect Med
Autors principals: Hainaut, Pierre, Pfeifer, Gerd P.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088513/
https://ncbi.nlm.nih.gov/pubmed/27503997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026179
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