Somatic Mosaic Mutations in PPM1D and TP53 in the Blood of Women With Ovarian Carcinoma

IMPORTANCE: Somatic mosaic mutations in PPM1D have been reported in patients with breast cancer, lung cancer, and ovarian cancer (OC), but cause or effect has not been established. OBSERVATIONS: To test the hypothesis that somatic mosaic mutations are associated with chemotherapy exposure, we used m...

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I publikationen:JAMA Oncol
Huvudupphovsmän: Swisher, Elizabeth M., Harrell, Maria I., Norquist, Barbara M., Walsh, Tom, Brady, Mark, Lee, Ming, Hershberg, Robert, Kalli, Kimberly R., Lankes, Heather, Konnick, Eric Q., Pritchard, Colin C., Monk, Bradley J., Chan, John K., Burger, Robert, Kaufmann, Scott H., Birrer, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865293/
https://ncbi.nlm.nih.gov/pubmed/26847329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.6053
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