Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

PURPOSE: The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the population and in a screening trial of individuals at high risk of ovarian cancer. PATIENTS AND METHODS: The coding sequ...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Song, Honglin, Dicks, Ed, Ramus, Susan J., Tyrer, Jonathan P., Intermaggio, Maria P., Hayward, Jane, Edlund, Christopher K., Conti, David, Harrington, Patricia, Fraser, Lindsay, Philpott, Susan, Anderson, Christopher, Rosenthal, Adam, Gentry-Maharaj, Aleksandra, Bowtell, David D., Alsop, Kathryn, Cicek, Mine S., Cunningham, Julie M., Fridley, Brooke L., Alsop, Jennifer, Jimenez-Linan, Mercedes, Høgdall, Estrid, Høgdall, Claus K., Jensen, Allan, Kjaer, Susanne Krüger, Lubiński, Jan, Huzarski, Tomasz, Jakubowska, Anna, Gronwald, Jacek, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B., Odunsi, Kunle, Goode, Ellen L., Menon, Usha, Jacobs, Ian J., Gayther, Simon A., Pharoah, Paul D.P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554751/
https://ncbi.nlm.nih.gov/pubmed/26261251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.2408
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