Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

PURPOSE: The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the population and in a screening trial of individuals at high risk of ovarian cancer. PATIENTS AND METHODS: The coding sequ...

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Publicado en:J Clin Oncol
Main Authors: Song, Honglin, Dicks, Ed, Ramus, Susan J., Tyrer, Jonathan P., Intermaggio, Maria P., Hayward, Jane, Edlund, Christopher K., Conti, David, Harrington, Patricia, Fraser, Lindsay, Philpott, Susan, Anderson, Christopher, Rosenthal, Adam, Gentry-Maharaj, Aleksandra, Bowtell, David D., Alsop, Kathryn, Cicek, Mine S., Cunningham, Julie M., Fridley, Brooke L., Alsop, Jennifer, Jimenez-Linan, Mercedes, Høgdall, Estrid, Høgdall, Claus K., Jensen, Allan, Kjaer, Susanne Krüger, Lubiński, Jan, Huzarski, Tomasz, Jakubowska, Anna, Gronwald, Jacek, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B., Odunsi, Kunle, Goode, Ellen L., Menon, Usha, Jacobs, Ian J., Gayther, Simon A., Pharoah, Paul D.P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554751/
https://ncbi.nlm.nih.gov/pubmed/26261251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.2408
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