Frequency of pathogenic germline variants in BRCA1, BRCA2, PALB2, CHEK2 and TP53 in ductal carcinoma in situ diagnosed in women under the age of 50 years

INTRODUCTION: Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal breast cancer, and approximately 20% of screen-detected tumours are pure DCIS. Most risk factors for breast cancer have similar associations with DCIS and IDC; however, there is limited data on the prevalenc...

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Udgivet i:Breast Cancer Res
Main Authors: Petridis, Christos, Arora, Iteeka, Shah, Vandna, Megalios, Anargyros, Moss, Charlotte, Mera, Anca, Clifford, Angela, Gillett, Cheryl, Pinder, Sarah E., Tomlinson, Ian, Roylance, Rebecca, Simpson, Michael A., Sawyer, Elinor J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501320/
https://ncbi.nlm.nih.gov/pubmed/31060593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1143-y
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