Downregulation of signal transducer and activator of transcription 3 by sorafenib: A novel mechanism for hepatocellular carcinoma therapy

по Hung, Man-Hsin, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Опубликовано в: World J Gastroenterol (2014)

Comment on “ALK is a therapeutic target for lethal sepsis”

по Blasco, Rafael B., Patrucco, Enrico, Mota, Ines, Tai, Wei-Tien, Chiarle, Roberto
Опубликовано в: Sci Transl Med (2018)

Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation

по Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Опубликовано 2013

Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

по Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Опубликовано 2013

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer()()

по Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Опубликовано в: Neoplasia (2015)

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

по Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Опубликовано в: Breast Cancer Res (2017)

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

по Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Опубликовано в: Oncotarget (2016)

Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody

по Chen, Kuen-Feng, Chen, Hui-Ling, Shiau, Chung-Wai, Liu, Chun-Yu, Chu, Pei-Yi, Tai, Wei-Tien, Ichikawa, Kimihisa, Chen, Pei-Jer, Cheng, Ann-Lii
Опубликовано 2013

SHP-1 is a target of regorafenib in colorectal cancer

по Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Опубликовано 2014

RFX1–dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells

по Su, Jung-Chen, Tseng, Ping-Hui, Hsu, Cheng-Yi, Tai, Wei-Tien, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Опубликовано 2014

SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma()()

по Su, Jung-Chen, Tseng, Ping-Hui, Wu, Szu-Hsien, Hsu, Cheng-Yi, Tai, Wei-Tien, Li, Yong-Shi, Chen, I-Ting, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Опубликовано 2014

SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A

по Hung, Man-Hsin, Wang, Cheng-Yi, Chen, Yen-Lin, Chu, Pei-Yi, Hsiao, Yung-Jen, Tai, Wei-Tien, Chao, Ting-Ting, Yu, Hui-Chuan, Shiau, Chung-Wai, Chen, Kuen-Feng
Опубликовано в: Oncotarget (2015)

SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma

по Tai, Wei-Tien, Hung, Man-Hsin, Chu, Pei-Yi, Chen, Yao-Li, Chen, Li-Ju, Tsai, Ming-Hsien, Chen, Min-Husan, Shiau, Chung-Wai, Boo, Yin-Pin, Chen, Kuen-Feng
Опубликовано в: Oncotarget (2016)

Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis

по Su, Jung-Chen, Mar, Ai-Chung, Wu, Szu-Hsien, Tai, Wei-Tien, Chu, Pei-Yi, Wu, Chia-Yun, Tseng, Ling-Ming, Lee, Te-Chang, Chen, Kuen-Feng, Liu, Chun-Yu, Chiu, Hao-Chieh, Shiau, Chung-Wai
Опубликовано в: Sci Rep (2016)

Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

по Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Liu, Chen-Hua, Liu, Chun-Jen, Tai, Wei-Tien, Jeng, Yung-Ming, Yang, Hung-Chih, Tseng, Tai-Chung, Huang, Hsiang-Po, Cheng, Huei-Ru, Chen, Pei-Jer, Chen, Kuen-Feng, Kao, Jia-Horng, Chen, Ding-Shinn
Опубликовано в: Proc Natl Acad Sci U S A (2015)

Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis

по Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Yang, Nian-Jie, Tai, Wei-Tien, Liu, Chun-Jen, Tseng, Tai-Chung, Yang, Hung-Chih, Liu, Chen-Hua, Huang, Kai-Wen, Hu, Ting-Chen, Huang, Yu-Jen, Wu, Yao-Ming, Chen, Li-Ju, Chen, Pei-Jer, Chen, Ding-Shinn, Chen, Kuen-Feng, Kao, Jia-Horng
Опубликовано в: Sci Rep (2017)