Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine

by Vanwalleghem, Gilles, Morias, Yannick, Beschin, Alain, Szymkowski, David E., Pays, Etienne
Published in Sci Rep (2017)

Suppression of innate and adaptive B cell activation pathways by antibody coengagement of FcγRIIb and CD19

by Szili, Dániel, Cserhalmi, Marcell, Bankó, Zsuzsanna, Nagy, György, Szymkowski, David E, Sármay, Gabriella
Published 2014

Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15

by Vujanovic, Lazar, Szymkowski, David E., Alber, Sean, Watkins, Simon C., Vujanovic, Nikola L., Butterfield, Lisa H.
Published 2010

Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia

by Karamita, Maria, Barnum, Christopher, Möbius, Wiebke, Tansey, Malú G., Szymkowski, David E., Lassmann, Hans, Probert, Lesley
Published in JCI Insight (2017)

Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis

by Oikonomou, Nikos, Harokopos, Vaggelis, Zalevsky, Jonathan, Valavanis, Christos, Kotanidou, Anastasia, Szymkowski, David E., Kollias, George, Aidinis, Vassilis
Published 2006

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

by Brambilla, Roberta, Ashbaugh, Jessica Jopek, Magliozzi, Roberta, Dellarole, Anna, Karmally, Shaffiat, Szymkowski, David E., Bethea, John R.
Published 2011

Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination

by Madsen, Pernille M., Motti, Dario, Karmally, Shaffiat, Szymkowski, David E., Lambertsen, Kate Lykke, Bethea, John R., Brambilla, Roberta
Published in J Neurosci (2016)

Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca(2+) Dysregulation in Aged Rats

by Sama, Diana M., Mohmmad Abdul, Hafiz, Furman, Jennifer L., Artiushin, Irina A., Szymkowski, David E., Scheff, Stephen W., Norris, Christopher M.
Published 2012

Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice

by Chu, Seung Y., Pong, Erik, Bonzon, Christine, Yu, Ning, Jacob, Chaim O., Chalmers, Samantha A., Putterman, Chaim, Szymkowski, David E., Stohl, William
Published in J Transl Autoimmun (2020)

Blocking Soluble Tumor Necrosis Factor Signaling with Dominant-Negative Tumor Necrosis Factor Inhibitor Attenuates Loss of Dopaminergic Neurons in Models of Parkinson's Disease

by McCoy, Melissa K., Martinez, Terina N., Ruhn, Kelly A., Szymkowski, David E., Smith, Christine G., Botterman, Barry R., Tansey, Keith E., Tansey, Malú G.
Published 2006

Topical Administration of a Soluble TNF Inhibitor Reduces Infarct Volume After Focal Cerebral Ischemia in Mice

by Yli-Karjanmaa, Minna, Clausen, Bettina Hjelm, Degn, Matilda, Novrup, Hans Gram, Ellman, Ditte Gry, Toft-Jensen, Peter, Szymkowski, David E., Stensballe, Allan, Meyer, Morten, Brambilla, Roberta, Lambertsen, Kate Lykke
Published in Front Neurosci (2019)

Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

by Novrup, Hans G, Bracchi-Ricard, Valerie, Ellman, Ditte G, Ricard, Jerome, Jain, Anjana, Runko, Erik, Lyck, Lise, Yli-Karjanmaa, Minna, Szymkowski, David E, Pearse, Damien D, Lambertsen, Kate L, Bethea, John R
Published 2014

Immune suppression in cynomolgus monkeys by XPro9523: An improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn

by Bernett, Matthew J., Chu, Seung Y., Leung, Irene, Moore, Gregory L., Lee, Sung-Hyung, Pong, Erik, Chen, Hsing, Phung, Sheryl, Muchhal, Umesh S., Horton, Holly M., Lazar, Greg A., Desjarlais, John R, Szymkowski, David E.
Published 2013

Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy

by Patel, Dipan C., Wallis, Glenna, Dahle, E. Jill, McElroy, Pallavi B., Thomson, Kyle E., Tesi, Raymond J., Szymkowski, David E., West, Peter J., Smeal, Roy M., Patel, Manisha, Fujinami, Robert S., White, H. Steve, Wilcox, Karen S.
Published in eNeuro (2017)

Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

by Clausen, Bettina Hjelm, Degn, Matilda, Martin, Nellie Anne, Couch, Yvonne, Karimi, Leena, Ormhøj, Maria, Mortensen, Maria-Louise Bergholdt, Gredal, Hanne Birgit, Gardiner, Chris, Sargent, Ian I L, Szymkowski, David E, Petit, Géraldine H, Deierborg, Tomas, Finsen, Bente, Anthony, Daniel Clive, Lambertsen, Kate Lykke
Published in J Neuroinflammation (2014)

Accelerated clearance and degradation of cell free HIV by neutralizing antibodies occurs via FcγRIIb on liver sinusoidal endothelial cells by endocytosis

by Turman, James M., Cheplowitz, Alana M., Tiwari, Charu, Thomas, Thushara, Joshi, Dhruvi, Bhat, Menakshi, Wu, Qian, Pong, Erik, Chu, Seung Y., Szymkowski, David E., Sharma, Amit, Seveau, Stephanie, Robinson, John M., Kwiek, Jesse J., Burton, Dennis, Rajaram, Murugesan VS., Kim, Jonghan, Hangartner, Lars, Ganesan, Latha P.
Published in J Immunol (2021)