Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination

Tumor necrosis factor (TNF) is associated with the pathophysiology of various neurological disorders, including multiple sclerosis. It exists as a transmembrane form tmTNF, signaling via TNF receptor 2 (TNFR2) and TNFR1, and a soluble form, solTNF, signaling via TNFR1. Multiple sclerosis is associat...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Madsen, Pernille M., Motti, Dario, Karmally, Shaffiat, Szymkowski, David E., Lambertsen, Kate Lykke, Bethea, John R., Brambilla, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854972/
https://ncbi.nlm.nih.gov/pubmed/27147664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0211-16.2016
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