Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

BACKGROUND: The innate immune system contributes to the outcome after stroke, where neuroinflammation and post-stroke systemic immune depression are central features. Tumor necrosis factor (TNF), which exists in both a transmembrane (tm) and soluble (sol) form, is known to sustain complex inflammato...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Clausen, Bettina Hjelm, Degn, Matilda, Martin, Nellie Anne, Couch, Yvonne, Karimi, Leena, Ormhøj, Maria, Mortensen, Maria-Louise Bergholdt, Gredal, Hanne Birgit, Gardiner, Chris, Sargent, Ian I L, Szymkowski, David E, Petit, Géraldine H, Deierborg, Tomas, Finsen, Bente, Anthony, Daniel Clive, Lambertsen, Kate Lykke
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272527/
https://ncbi.nlm.nih.gov/pubmed/25498129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0203-6
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