Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

BACKGROUND: Glial cell activation and overproduction of inflammatory mediators in the central nervous system (CNS) have been implicated in acute traumatic injuries to the CNS, including spinal cord injury (SCI). Elevated levels of the proinflammatory cytokine tumor necrosis factor (TNF), which exist...

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Detalhes bibliográficos
Main Authors: Novrup, Hans G, Bracchi-Ricard, Valerie, Ellman, Ditte G, Ricard, Jerome, Jain, Anjana, Runko, Erik, Lyck, Lise, Yli-Karjanmaa, Minna, Szymkowski, David E, Pearse, Damien D, Lambertsen, Kate L, Bethea, John R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176557/
https://ncbi.nlm.nih.gov/pubmed/25204558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0159-6
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