Niemann–Pick type C pathogenesis and treatment: from statins to sugars

Por Madra, Moneek, Sturley, Stephen L
Publicado em 2010

The genetics of neutral lipid biosynthesis: an evolutionary perspective

Por Turkish, Aaron R., Sturley, Stephen L.
Publicado em 2009

Lipid droplet formation on opposing sides of the endoplasmic reticulum

Por Sturley, Stephen L., Hussain, M. Mahmood
Publicado em 2012

Unraveling the sterol-trafficking defect in Niemann-Pick C disease

Por Sturley, Stephen L., Patterson, Marc C., Pentchev, Peter
Publicado em 2009

Exacerbating and reversing lysosomal storage diseases: from yeast to humans

Por Rajakumar, Tamayanthi, Munkacsi, Andrew B., Sturley, Stephen L.
Publicado no Microb Cell (2017)

Niemann–Pick type C disease proteins: orphan transporters or membrane rheostats?

Por Munkacsi, Andrew B, Porto, Anthony F, Sturley, Stephen L
Publicado em 2007

Transcriptional Regulation of the Two Sterol Esterification Genes in the Yeast Saccharomyces cerevisiae

Por Jensen-Pergakes, Kristen, Guo, Zhongmin, Giattina, Mara, Sturley, Stephen L., Bard, Martin
Publicado em 2001

Sterols and sphingolipids: Dynamic duo or partners in crime?

Por Gulati, Sonia, Liu, Ying, Munkacsi, Andrew B., Wilcox, Lisa, Sturley, Stephen L.
Publicado em 2010

Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast

Por Fakas, Stylianos, Qiu, Yixuan, Dixon, Joseph L., Han, Gil-Soo, Ruggles, Kelly V., Garbarino, Jeanne, Sturley, Stephen L., Carman, George M.
Publicado em 2011

Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism

Por Tong, Fumin, Billheimer, Jeffrey, Shechtman, Caryn F., Liu, Ying, Crooke, Roseann, Graham, Mark, Cohen, David E., Sturley, Stephen L., Rader, Daniel J.
Publicado em 2010

Sterol and Diacylglycerol Acyltransferase Deficiency Triggers Fatty Acid-mediated Cell Death

Por Garbarino, Jeanne, Padamsee, Mahajabeen, Wilcox, Lisa, Oelkers, Peter M., D'Ambrosio, Diana, Ruggles, Kelly V., Ramsey, Nicole, Jabado, Omar, Turkish, Aaron, Sturley, Stephen L.
Publicado em 2009

Cumulative Mutations Affecting Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae Result in Synthetic Lethality That Is Suppressed by Alterations in Sphingolipid Profiles

Por Valachovic, Martin, Bareither, Bart M., Bhuiyan, M. Shah Alam, Eckstein, James, Barbuch, Robert, Balderes, Dina, Wilcox, Lisa, Sturley, Stephen L., Dickson, Robert C., Bard, Martin
Publicado em 2006

Loss of Subcellular Lipid Transport Due to ARV1 Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response

Por Shechtman, Caryn F., Henneberry, Annette L., Seimon, Tracie A., Tinkelenberg, Arthur H., Wilcox, Lisa J., Lee, Eunjee, Fazlollahi, Mina, Munkacsi, Andrew B., Bussemaker, Harmen J., Tabas, Ira, Sturley, Stephen L.
Publicado em 2011

An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C...

Por Munkacsi, Andrew B., Chen, Fannie W., Brinkman, Matthew A., Higaki, Katsumi, Gutiérrez, Giselle Domínguez, Chaudhari, Jagruti, Layer, Jacob V., Tong, Amy, Bard, Martin, Boone, Charles, Ioannou, Yiannis A., Sturley, Stephen L.
Publicado em 2011

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

Por Area-Gomez, Estela, del Carmen Lara Castillo, Maria, Tambini, Marc D, Guardia-Laguarta, Cristina, de Groof, Ad J C, Madra, Moneek, Ikenouchi, Junichi, Umeda, Masato, Bird, Thomas D, Sturley, Stephen L, Schon, Eric A
Publicado em 2012

Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C–related protein reveals a primordial role in subcellular sphingolipid distribution

Por Malathi, Krishnamurthy, Higaki, Katsumi, Tinkelenberg, Arthur H., Balderes, Dina A., Almanzar-Paramio, Dorca, Wilcox, Lisa J., Erdeniz, Naz, Redican, Francis, Padamsee, Mahajabeen, Liu, Ying, Khan, Sohail, Alcantara, Frederick, Carstea, Eugene D., Morris, Jill A., Sturley, Stephen L.
Publicado em 2004

A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “ARE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistanc...

Por Ruggles, Kelly V., Garbarino, Jeanne, Liu, Ying, Moon, James, Schneider, Kerry, Henneberry, Annette, Billheimer, Jeff, Millar, John S., Marchadier, Dawn, Valasek, Mark A., Joblin-Mills, Aidan, Gulati, Sonia, Munkacsi, Andrew B., Repa, Joyce J., Rader, Dan, Sturley, Stephen L.
Publicado em 2014

ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification

Por Gulati, Sonia, Balderes, Dina, Kim, Christine, Guo, Zhongmin A., Wilcox, Lisa, Area-Gomez, Estela, Snider, Jamie, Wolinski, Heimo, Stagljar, Igor, Granato, Juliana T., Ruggles, Kelly V., DeGiorgis, Joseph A., Kohlwein, Sepp D., Schon, Eric A., Sturley, Stephen L.
Publicado no FASEB J (2015)

Normalization of Hepatic Homeostasis in the Npc1(nmf164) Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat

Por Munkacsi, Andrew B., Hammond, Natalie, Schneider, Remy T., Senanayake, Dinindu S., Higaki, Katsumi, Lagutin, Kirill, Bloor, Stephen J., Ory, Daniel S., Maue, Robert A., Chen, Fannie W., Hernandez-Ono, Antonio, Dahlson, Nicole, Repa, Joyce J., Ginsberg, Henry N., Ioannou, Yiannis A., Sturley, Stephen L.
Publicado no J Biol Chem (2017)

Mapping the functional yeast ABC transporter interactome

Por Snider, Jamie, Hanif, Asad, Lee, Mid Eum, Jin, Ke, Yu, Analyn R., Graham, Chris, Chuk, Matthew, Damjanovic, Dunja, Wierzbicka, Marta, Tang, Priscilla, Balderes, Dina, Wong, Victoria, Jessulat, Matthew, Darowski, Katelyn D., Luis, Bryan-Joseph San, Shevelev, Igor, Sturley, Stephen L, Boone, Charles, Greenblatt, Jack F., Zhang, Zhaolei, Paumi, Christian M., Babu, Mohan, Park, Hay-Oak, Michaelis, Susan, Stagljar, Igor
Publicado em 2013