Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast

The PAH1-encoded phosphatidate (PA) phosphatase in Saccharomyces cerevisiae is a pivotal enzyme that produces diacylglycerol for the synthesis of triacylglycerol (TAG) and simultaneously controls the level of PA used for phospholipid synthesis. Quantitative lipid analysis showed that the pah1Δ mutat...

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Detalhes bibliográficos
Main Authors: Fakas, Stylianos, Qiu, Yixuan, Dixon, Joseph L., Han, Gil-Soo, Ruggles, Kelly V., Garbarino, Jeanne, Sturley, Stephen L., Carman, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190715/
https://ncbi.nlm.nih.gov/pubmed/21708942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258798
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