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Niemann–Pick type C disease proteins: orphan transporters or membrane rheostats?
Niemann–Pick type C (NPC) disease is a panethnic lysosomal lipidosis, which results in severe cerebellar impairment and death, and is proposed to be a consequence of defective metabolite transport. Numerous models of this disorder have defined the phenotypic impact of misfunction of the NPC proteins...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704495/ https://ncbi.nlm.nih.gov/pubmed/19578548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/17460875.2.3.357 |
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