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Niemann–Pick type C pathogenesis and treatment: from statins to sugars
The isolation of the causative genes for Niemann–Pick type C disease, a panethnic lysosomal lipid storage disorder, has provided models of how sterols and other lipids such as glycosphingolipids traverse the membranes of eukaryotic cells. Unfortunately, these molecular advances have yet to reciproca...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050622/ https://ncbi.nlm.nih.gov/pubmed/21394236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/clp.10.19 |
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