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The pathogenesis of Niemann-Pick type C disease: a role for autophagy?
Niemann-Pick type C disease (NPC) is a sphingolipid storage disorder that results from inherited deficiencies of intracellular lipid trafficking proteins, and is characterized by an accumulation of cholesterol and glycosphingolipids in late endosomes and lysosomes. Patients with this disorder develo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662713/ https://ncbi.nlm.nih.gov/pubmed/18782459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S146239940800080X |
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