Laddar...
Impaired proteolysis underlies autophagic dysfunction in Niemann–Pick type C disease
Niemann–Pick type C disease (NPC) is a childhood onset neurodegenerative disorder arising from lipid-trafficking defects caused by mutations in the NPC1 or NPC2 gene. Marked accumulation of autophagosomes is a prominent feature of NPC cells, yet a detailed understanding of the disease-associated alt...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2012
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607480/ https://ncbi.nlm.nih.gov/pubmed/22872701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds324 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|