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Autophagic dysfunction in a lysosomal storage disorder due to impaired proteolysis

Alterations in macroautophagy (hereafter referred to as “autophagy”) are a common feature of lysosomal storage disorders, and have been hypothesized to play a major role in the pathogenesis of these diseases. We have recently reported multiple defects in autophagy contributing to the lysosomal stora...

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Detalhes bibliográficos
Main Authors: Elrick, Matthew J., Lieberman, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552886/
https://ncbi.nlm.nih.gov/pubmed/23086309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22501
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