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Autophagic dysfunction in a lysosomal storage disorder due to impaired proteolysis
Alterations in macroautophagy (hereafter referred to as “autophagy”) are a common feature of lysosomal storage disorders, and have been hypothesized to play a major role in the pathogenesis of these diseases. We have recently reported multiple defects in autophagy contributing to the lysosomal stora...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552886/ https://ncbi.nlm.nih.gov/pubmed/23086309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22501 |
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