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Localization of Niemann–Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann– Pick type C disease

Niemann–Pick type C disease (NP-C) is an inherited neurovisceral lipid storage disorder characterized by progressive neurodegeneration. Most cases of NP-C result from inactivating mutations of NPC1, a recently identified member of a family of genes encoding membrane-bound proteins containing putativ...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Patel, Shutish C., Suresh, Sundar, Kumar, Ujendra, Hu, C. Y., Cooney, Adele, Blanchette-Mackie, E. Joan, Neufeld, Edward B., Patel, Ramesh C., Brady, Roscoe O., Patel, Yogesh C., Pentchev, Peter G., Ong, Wei-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1657
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