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Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease
Niemann–Pick type C1 (NPC1) disease results from a defect in the NPC1 protein and is characterized by a pathological accumulation of cholesterol and glycolipids in endocytic organelles. We followed the biosynthesis and trafficking of NPC1 with the use of a functional green fluorescent protein-fused...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31858/ https://ncbi.nlm.nih.gov/pubmed/11296289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081070898 |
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