Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype

Patients treated with amiodarone accumulate lysobisphosphatidic acid (LBPA), also known as bis(monoacylglycero)phosphate, in airway secretions and develop in different tissues vacuoles and inclusion bodies thought to originate from endosomes. To clarify the origin of these changes, we studied in vit...

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Detaylı Bibliyografya
Yayımlandı:Biochem Pharmacol
Asıl Yazarlar: Piccoli, Elena, Nadai, Matteo, Caretta, Carla Mucignat, Bergonzini, Valeria, Del Vecchio, Claudia, Ha, Huy Riem, Bigler, Laurent, Dal Zoppo, Daniele, Faggin, Elisabetta, Pettenazzo, Andrea, Orlando, Rocco, Salata, Cristiano, Calistri, Arianna, Palù, Giorgio, Baritussio, Aldo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Inc. 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092840/
https://ncbi.nlm.nih.gov/pubmed/21878321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.07.090
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