Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype

Patients treated with amiodarone accumulate lysobisphosphatidic acid (LBPA), also known as bis(monoacylglycero)phosphate, in airway secretions and develop in different tissues vacuoles and inclusion bodies thought to originate from endosomes. To clarify the origin of these changes, we studied in vit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Pharmacol
Päätekijät: Piccoli, Elena, Nadai, Matteo, Caretta, Carla Mucignat, Bergonzini, Valeria, Del Vecchio, Claudia, Ha, Huy Riem, Bigler, Laurent, Dal Zoppo, Daniele, Faggin, Elisabetta, Pettenazzo, Andrea, Orlando, Rocco, Salata, Cristiano, Calistri, Arianna, Palù, Giorgio, Baritussio, Aldo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Inc. 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092840/
https://ncbi.nlm.nih.gov/pubmed/21878321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.07.090
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